Atypical Hemolytic Uremic Syndrome (aHUS)
Home Atypical Hemolytic Uremic Syndrome (aHUS)
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0Which of the following can be signs and symptoms of aHUS?
To learn more, choose the answer that you find the most likely:
- a Thrombocytopenia and anemia
- b Renal insufficiency
- c Extra-renal manifestations (eg, central nervous system involvement, cardiovascular manifestations)
- d All of the above
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Patients with aHUS typically present with thrombocytopenia, hemolytic anemia and renal insufficiency.1,2 Extra-renal manifestations are also seen in approximately 20% of patients.1,2 There is no singular diagnostic criterion for aHUS, so the first step in diagnosis is to exclude other causes of TMA.1,2 Complement genetic testing identifying a pathogenic mutation, or complement serology showing abnormalities in the alternative pathway, can support the diagnosis of aHUS.1,2
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